Academic Appointments
- Associate Research Scientist in the Department of Otolaryngology - Head & Neck Surgery
Hunki Paek, Ph.D., currently serves as Associate Research Scientist at Columbia University Medical Center, where he specializes in basic science research regarding the hearing loss and potential therapy. Dr. Hunki Paek graduated from Korea University and obtained his Ph.D. of Genetics and Neuroscience in Albert Einstein College of Medicine. After his Ph.D. he started to work at Columbia University Medical Center investigating cell surface markers of putative quiescent adult neural stem cells from their in vivo niche and characterizing a novel protein PDZD8 involved in ER-Mitochondrial tethering of neurons in the mouse brain. At Columbia University Medical Center the research of Dr. Hunki Paek is focused on understanding cellular and molecular changes in the peripheral/central auditory system in response to noise-induced hearing loss.
Languages Spoken
- Korean
Lab Locations
Columbia University Vagelos College of Physicians and Surgeons
630 West 168th Street
9th floor
New York, NY 10032- Lab Phone:
- (212) 305-6923
Contact Info
- (212) 305-6923
NIH Grants
MECHANISMS OF AXON GUIDANCE IN LARYNGEAL REINNERVATION FOLLOWING INJURY OF THE RECURRENT LARYNGEAL NERVE (Federal Gov)
Jul 1 2019 - Jun 30 2024
CONTRIBUTION OF GENETIC FACTORS TO SUDDEN NOISE-INDUCED HEARING LOSS (NY State Gov)
Apr 1 2015 - Jun 30 2019
PROSPECTIVE PURIFICATION OF ADULT STEM CELL ASTROCYTES (Federal Gov)
Sep 1 2011 - May 31 2017
MICRORNA REGULATION OF ADULT NEURAL STEM CELLS (NY State Gov)
Mar 1 2013 - Feb 28 2016
THREE DIMENSIONAL HIGH RESOLUTION RECONSTRUCTION OF THE INVIVO ADULT NEURAL STEM CELL NICHE (NY State Gov)
Mar 1 2013 - May 31 2013
MOLECULAR PROFILING AND DIFFERENTIATION POTENTIAL OF PURIFIE D ADULT NEURAL STEM CELL LINEAGES (NY State Gov)
Jan 1 2009 - Jun 30 2011
Publications
1. Hirabayashi, Y.*, Kwon, S.*, Paek, H., Pernice, W., Paul, M., Lee, J., Erfani, P., Raczkowski, A., Petrey, D., Pon, L. and Polleux F. ER-mitochondria tethering by PDZD8 regulates
Ca2+ dynamics in mammalian neurons (2017). Science 358, 623-630. (*Co-first authors)
2. Paek, H., Antoine, M., Diaz, F. and Hébert, J. M. Increased ?-catenin activity in the anterior neural plate induces ectopic mid-hindbrain characteristics (2012). Developmental Dynamics 241, 242-246
3. Paek, H., Hwang,J., Zukin, S. and Hébert, J. M. (2011) ?-catenin-dependent FGF signaling sustains cell survival in the anterior embryonic head by countering Smad4. Developmental cell 20,689-699.
4. Maier, E., von Hofsten, J., Nord, H., Fernandes,M., Paek, H., Hébert, J. M. and Gunhaga, L. (2010). Opposing activities of FGF and BMP regulate the olfactory sensory versus respiratory epithelial cell fate decision. Development 137, 1601-1611.
5. Paek, H., Gutin, G. and Hébert, J. M. (2009). FGF signaling is strictly required to maintain early telencephalic precursor cell survival. Development 136, 2457-2465.
6. Gutin, G., Fernandes, M., Palazzolo, L., Paek, H., Yu, K., Ornitz, D. M., McConnell, S. K. and Hébert, J. M. (2006). FGF signaling generates ventral telencephalic cells independently of SHH. Development 133, 2937-2946.